Transmission of tuberculosis from smear negative patients: a molecular epidemiology study

TUBERCULOSIS Transmission of tuberculosis from smear negative patients: a molecular epidemiology study

Background: While smear positive patients with tuberculosis (TB) are considered more infectious than smear negative patients, the latter can also transmit TB. Methods: In a molecular epidemiology study of 791 patients in the Greater Vancouver regional district, the number of episodes of TB transmission from two groups of smear negative clustered patients by RFLP (assumed to be involved in recen...

Transmission of tuberculosis from smear negative patients: a molecular epidemiology study.

BACKGROUND While smear positive patients with tuberculosis (TB) are considered more infectious than smear negative patients, the latter can also transmit TB. METHODS In a molecular epidemiology study of 791 patients in the Greater Vancouver regional district, the number of episodes of TB transmission from two groups of smear negative clustered patients by RFLP (assumed to be involved in recen...

Tuberculosis transmission by patients with smear-negative pulmonary tuberculosis in a large cohort in the Netherlands.

BACKGROUND Sputum smear microscopy is commonly used for diagnosing tuberculosis (TB). Although patients with sputum smear-negative TB are less infectious than patients with smear-positive TB, they also contribute to TB transmission. The objective of this study was to determine the proportion of TB transmission events caused by patients with smear-negative pulmonary TB in The Netherlands. METH...

The role of bronchoscopy in diagnosis of tuberculosis in patients with negative smear & culture

tuberculosis (TB) is a serious health problem in the world.in 1990 among 5.5 million population in the world,nearly 7.5 million new cases reported and 3 million  patients expired due to this problem.because early detectio of TB is very important ,we decided to evaluate the role of fiberoptic bronchoscopy(FOB) in detection of TB in patients with negative smear and negative culture of sputum.in t...

Molecular epidemiology of intra-familial tuberculosis transmission.